CSFP Research News

July 11, 2011

Respiratory Medicine Prize awarded to MMI Clinician Scientist Fellow

  From left to right: Guen Flanagan (Mundiharma Pharmaceuticals) Dr Sanjay Chotirmall (RCSI) and Prof Tom Walsh (President of the Royal Academy of Medicine in Ireland) […]
April 12, 2011

Top Prize won by MMI Clinician Scientist Fellow at American Cardiology Meeting

Dr John O'Sullivan (pictured left) who is an MMI Clinician Scientist Fellow won the Young Investigator Award at the American College of Cardiology Meeting in New Orleans this week for groundbreaking work carried out in University College Cork (UCC).

October 1, 2010

MMI Clinician Scientist Fellow involved in research breakthrough in understanding gender gap in cystic fibrosis

Researchers at the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital including MMI Clinician Scientist Fellow Dr Sanjay Chotirmall (pictured left) have made a major breakthrough in understanding how female sufferers of cystic fibrosis (CF) fare worse compared to male sufferers due to higher levels of the hormone oestrogen. The new insights into the mechanisms at work in CF revealed from this research may lead to new treatments for the disease.

June 30, 2010

Predictive Biomarkers in Breast Cancer Discovered by Research Team including MMI Clinician Scientist Fellow

Predictive Biomarkers in Breast Cancer Discovered by Research Team including MMI Clinician Scientist FellowA team led by Dr Leonie Young of RCSI including MMI Clinician Scientist Fellow Dr Damian McCartan and researchers based in UCD has published important research with applications in the diagnosis and treatment of breast cancer. About 70% of breast cancers are oestrogen receptor positive ? the cancer cells contain oestrogen hormone receptors and the hormone stimulates the cancer cells to multiply. Standard therapy incorporates treatments to reduce the level of oestrogen or block its action on cells. However in some cases (25-30%) the cancer re-grows. The team have discovered two predictive biomarkers one in tissue and the other in blood serum that can give advance warning if a patient is likely to have a poor response to standard therapies. This enables the clinician to select an alternative more aggressive therapy at an earlier stage. The College recently launched the research findings and is hoping to develop a test with a commercial partner.The research was supported by Science Foundation Ireland and Breast Cancer Ireland. Dr Damian McCartan holds an MMI Clinician Scientist Fellowship. The MMI Clinician Scientist Fellowship Programme is funded through PRTLI Cycle 4 administered by the Higher Education Authority.LinksIrish Times article: http://www.irishtimes.com/newspaper/ireland/2010/0525/1224271087415.htmlResearch publication:McIlroy M McCartan D Early S Gaora PO Pennington S Hill AD Young LS. (2010). Interaction of Developmental Transcription Factor HOXc11 with Steroid Receptor Coactivator SRC-1 Mediates Resistance to Endocrine Therapy in Breast Cancer. Cancer Res. 70 1585-1594. http://cancerres.aacrjournals.org/cgi/content/abstract/70/4/1585MMI Clinician Scientist Fellowship Programme: https://www.crdi.ie/csfp
January 18, 2010

MMI Clinician Scientist Fellow involved in ground-breaking breast cancer research

Ground breaking research from the Breast Cancer Research Group in NUI Galway, demonstrating that microRNAs are measurable in the blood of breast cancer patients and suggesting […]