June 30, 2010

DCCR contract finalised

June 30, 2010

Predictive Biomarkers in Breast Cancer Discovered by Research Team including MMI Clinician Scientist Fellow

Predictive Biomarkers in Breast Cancer Discovered by Research Team including MMI Clinician Scientist FellowA team led by Dr Leonie Young of RCSI including MMI Clinician Scientist Fellow Dr Damian McCartan and researchers based in UCD has published important research with applications in the diagnosis and treatment of breast cancer. About 70% of breast cancers are oestrogen receptor positive ? the cancer cells contain oestrogen hormone receptors and the hormone stimulates the cancer cells to multiply. Standard therapy incorporates treatments to reduce the level of oestrogen or block its action on cells. However in some cases (25-30%) the cancer re-grows. The team have discovered two predictive biomarkers one in tissue and the other in blood serum that can give advance warning if a patient is likely to have a poor response to standard therapies. This enables the clinician to select an alternative more aggressive therapy at an earlier stage. The College recently launched the research findings and is hoping to develop a test with a commercial partner.The research was supported by Science Foundation Ireland and Breast Cancer Ireland. Dr Damian McCartan holds an MMI Clinician Scientist Fellowship. The MMI Clinician Scientist Fellowship Programme is funded through PRTLI Cycle 4 administered by the Higher Education Authority.LinksIrish Times article: http://www.irishtimes.com/newspaper/ireland/2010/0525/1224271087415.htmlResearch publication:McIlroy M McCartan D Early S Gaora PO Pennington S Hill AD Young LS. (2010). Interaction of Developmental Transcription Factor HOXc11 with Steroid Receptor Coactivator SRC-1 Mediates Resistance to Endocrine Therapy in Breast Cancer. Cancer Res. 70 1585-1594. http://cancerres.aacrjournals.org/cgi/content/abstract/70/4/1585MMI Clinician Scientist Fellowship Programme: https://www.crdi.ie/csfp
June 30, 2010

TCD & UCD Researchers Discover New Autism Genes as Part of Major International Research Project

New autism genes have been discovered by researchers at Trinity College Dublin and University College Dublin as part of a Global Autism Genome Project involving 50 […]
June 30, 2010

Irish scientists uncover genetic secrets of human adaptation to high altitude

A group of top international scientists including geneticists from the Royal College of Surgeons in Ireland (RCSI) has made a breakthrough in understanding human adaptation to […]
June 30, 2010

Science Bus travels to Turin to promote Dublin as European City of Science in 2012

June 29, 2010

MMI CSFP Annual Meeting 2010

Macrophage cell death is tightly coupled with the performance of microbicidal function during innate immune responses.
June 26, 2010

CSFP Annual Meeting 2010

The CSFP Annual Meeting gathered key individuals involved in this MMI programme including the Fellows’ supervisors. This second Annual Meeting took place on Friday 25 June 2010 […]
June 21, 2010

SFI/MMI Technology Platform Workshop June 3rd 2010

June 18, 2010

MMI Clinician Scientist Fellowship Programme 2nd Annual Meeting

The second Annual Meeting of MMI Clinician Scientist Fellowship Programme will take place in University College Cork on 25 June 2010. The format will be similar to last year's very successful meeting held in NUI Galway.
June 17, 2010

HRB – TCD Doctoral Programme in Molecular Medicine Keynote Public Lecture